US Patent Issued to Massachusetts Institute of Technology on Oct. 28 for "Ligand discovery and gene delivery via retroviral surface display" (Massachusetts Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,455,280, issued on Oct. 28, was assigned to Massachusetts Institute of Technology (Cambridge, Mass.).

"Ligand discovery and gene delivery via retroviral surface display" was invented by Michael Birnbaum (Arlington, Mass.) and Connor Dobson (Somerville, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions of retroviruses and methods of using the same for gene delivery, wherein the retroviruses comprise a viral envelope protein comprising at least one mutation that diminishes its native function, a non-viral membrane-bound protein comprising a membrane-bound domain and an extracellular targeting domain."

The patent was filed on Jan. 9, 2025,...