ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,480,079, issued on Nov. 25, was assigned to Massachusetts Institute of Technology (Cambridge, Mass.).
"Fluidic platforms for perfusable vascularized tissues with infiltrates" was invented by Roger Kamm (Cambridge, Mass.), Huu Tuan Nguyen (Cambridge, Mass.) and Sharon Wei Ling Lee (Cambridge, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Microfluidic devices with open ports and gel channels for forming perfusable hydrogel vascular networks with holes or ports for samples, and methods of making and using, are provided which integrate interstitial flows to an ex vivo vascularized tissue model. Samples of cells, spheroids, organoids, and tissues can ...