US Patent Issued to Massachusetts Institute of Technology on May 13 for "High performance multi-input microRNA sensors and uses thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,506, issued on May 13, was assigned to Massachusetts Institute of Technology (Cambridge, Mass.).

"High performance multi-input microRNA sensors and uses thereof" was invented by Ron Weiss (Newton, Mass.) and Jin Huh (Watertown, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are genetic circuits and cell state classifiers for detecting the microRNA profile of a cell. The cell state classifiers of the present disclosure are designed to incorporate multiple genetic circuits integrated together by transcriptional or translational control. Multiple inputs can be sensed simultaneously by coupling their detection to different portions...