US Patent Issued to Massachusetts Institute of Technology on June 3 for "Methods to spatially profile protease activity in tissue and sections" (Massachusetts Inventors)

ALEXANDRIA, Va., June 4 -- United States Patent no. 12,320,801, issued on June 3, was assigned to Massachusetts Institute of Technology (Cambridge, Mass.).

"Methods to spatially profile protease activity in tissue and sections" was invented by Sangeeta N. Bhatia (Lexington, Mass.), Jaideep S. Dudani (Cambridge, Mass.), Ester J. Kwon (Cambridge, Mass.) and Andrew David Warren (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Aspects of the disclosure relate to methods and compositions useful for in vivo and/or in vitro enzyme profiling. In some embodiments, the disclosure provides methods of in vivo enzymatic processing of exogenous molecules followed by detection of signature molecules as repr...