US Patent Issued to Massachusetts Institute of Technology on Jan. 28 for "Engineered Herpes Simplex Virus-1 (HSV-1) vectors and uses thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., Jan. 29 -- United States Patent no. 12,209,250, issued on Jan. 28, was assigned to Massachusetts Institute of Technology (Cambridge, Mass.).

"Engineered Herpes Simplex Virus-1 (HSV-1) vectors and uses thereof" was invented by Ron Weiss (Newton, Mass.), Maria Hottelet Foley (Cambridge, Mass.), Jin Huh (Watertown, Mass.) and Ross D. Jones (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are engineered HSV-1 vectors comprising a modified HSV-1 genome. The engineered HSV-1 vectors can be used to deliver genetic circuits (e.g., up to 100 kb) to cells in vitro or in vivo. Methods of treating or diagnosing a disease (e.g., cancer) using the engineered HSV-1 vectors d...