US Patent Issued to Massachusetts Eye and Ear Infirmary on Sept. 30 for "Sensorineural hair cell differentiation" (Massachusetts Inventors)

ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,427,128, issued on Sept. 30, was assigned to Massachusetts Eye and Ear Infirmary (Boston).

"Sensorineural hair cell differentiation" was invented by Albert Edge (Brookline, Mass.), Judith Kempfle (Brookline, Mass.) and Dunia Abdul-Aziz (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides compositions and methods for treating subjects at risk for or with sensorineural hearing loss. Such compositions and methods include modulating the epigenetic status of the cell, or rate of protein degradation, to increase expression and/or levels of Atoh1 protein."

The patent was filed on March 30, 2022, under Application No. 17/708,...