US Patent Issued to Massachusetts Eye and Ear Infirmary, Editas Medicine on June 17 for "CRISPR/Cas9-mediated exon-skipping approach for USH2A-associated usher syndrome" (Massachusetts Inventors)

ALEXANDRIA, Va., June 19 -- United States Patent no. 12,331,328, issued on June 17, was assigned to Massachusetts Eye and Ear Infirmary (Boston) and Editas Medicine Inc. (Cambridge, Mass.).

"CRISPR/Cas9-mediated exon-skipping approach for USH2A-associated usher syndrome" was invented by Eric A. Pierce (Boston), Carrie Marie Margulies (Newton, Mass.), Nachiket D. Pendse (Quincy, Mass.), Sebastian W. Gloskowski (Malden, Mass.), Qin Liu (Boston) and Morgan L. Maeder (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions for use in treating subjects with USH2A-associated retinal and/or cochlear degeneration that result from mutations in exon 13 of the USH2A gene by deletion of exon 13 from...