ALEXANDRIA, Va., June 4 -- United States Patent no. 12,318,504, issued on June 3, was assigned to Marine Biomedical Pty Ltd (Perth, Australia).
"Method for manufacturing a calcified tissue substitute" was invented by Rui Ruan (Nedlands, Australia) and Ming-Hao Zheng (City Beach, Australia).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a method for manufacturing a calcified tissue substitute, the method comprising: reacting ground nacre, monocalcium phosphate, and water to produce brushite; grinding the brushite; reacting ground nacre with the ground brushite in disodium hydrogenphosphate solution. The invention also relates to a calcified tissue substitute manufactured by the method,...