US Patent Issued to Marengo Therapeutics on March 11 for "Calreticulin binding constructs and engineered T cells for the treatment of diseases" (Massachusetts Inventors)

ALEXANDRIA, Va., March 12 -- United States Patent no. 12,247,060, issued on March 11, was assigned to Marengo Therapeutics Inc. (Cambridge, Mass.).

"Calreticulin binding constructs and engineered T cells for the treatment of diseases" was invented by Andreas Loew (Cambridge, Mass.) and Brian Edward Vash (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are nucleic acid constructs, polypeptides and T cells related to antigen binding domains that bind to mutant calreticulin; and methods of use thereof for the treatment of diseases, including cancer."

The patent was filed on Jan. 9, 2019, under Application No. 16/960,704.

*For further information, including images, charts and ta...