ALEXANDRIA, Va., March 19 -- United States Patent no. 12,251,380, issued on March 18, was assigned to Mapi Pharma Ltd. (Ness Ziona, Israel).

"Depot systems comprising cariprazine or salts thereof" was invented by Shai Rubnov (Tel Aviv, Israel), Ehud Marom (Tel Aviv, Israel) and Anna Gopin (Petah-Tiqwa, Israel).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides long-acting parenteral pharmaceutical compositions including a therapeutically effective amount of Cariprazine or salts thereof, in a depot form suitable for administering at a medically acceptable location in a subject in need thereof. The depot compositions are preferably in the form of in-situ implants suitable for subcutan...