US Patent Issued to MABPLEX INTERNATIONAL on Jan. 27 for "Antibody drug conjugate loaded with binary toxins and its application" (Chinese Inventors)

ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,533,419, issued on Jan. 27, was assigned to MABPLEX INTERNATIONAL Co. LTD. (Shandong, China).

"Antibody drug conjugate loaded with binary toxins and its application" was invented by Changjiang Huang (Shandong, China), Youxiang Sun (Shandong, China), Jiukai Xiong (Shandong, China), Nana Kong (Shandong, China) and Xinxin Yan (Shandong, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides an antibody-drug conjugate loaded with binary toxins. By connecting MMAF with another drug unit in series at the cysteine binding site on the antibody, the two can exert a significant synergistic effect, thereby effectively improving the ef...