ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,492,412, issued on Dec. 9, was assigned to M6P TERAPEUTICS (SWITZERLAND) LLC (Schaffhausen, Switzerland).
"Vector compositions and methods of using same for treatment of lysosomal storage disorders" was invented by Cuong Do (Mendham, N.J.) and Lin Liu (St. Louis).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are compositions and methods of using a bicistronic vector for treating or preventing a lysosomal storage disorder (LSD) in a subject. The disclosed compositions comprise a bicistronic vector comprising a promoter, an Internal Ribosome Entry Site (IRES), a polynucleotide encoding a lysosomal enzyme and a polynucleotide encoding a modi...