ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,332, issued on March 25, was assigned to Lycia Therapeutics Inc. (South San Francisco, Calif.).
"ASGPR cell surface receptor binding compounds and conjugates" was invented by Brett Bradley Busch (San Diego), Justin Thomas Ernst (San Diego), Garrick K. Packard (San Diego), Jason G. Lewis (Castro Valley, Calif.) and Eric D. Turtle (Belmont, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a class of compounds including a ligand moiety that specifically binds to a cell surface asialoglycoprotein receptor (ASGPR). The cell surface ASGPR binding compounds can trigger the receptor to internalize into the cell a bound ...