ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,480,152, issued on Nov. 25, was assigned to LUMINEX Corp. (Austin, Texas).
"Probes for improved melt discrimination and multiplexing in nucleic acid assays" was invented by Scott C. Johnson (Austin, Texas), Nicolas Arab (Austin, Texas) and Doug Whitman (Round Rock, Texas).
According to the abstract* released by the U.S. Patent & Trademark Office: "Methods and compositions for the detection and quantification of nucleic acids are provided. In certain embodiments, methods involve the use of cleavable probes that comprise a ribonucleotide position that is susceptible to endoribonuclease (e.g., RNase H) cleavage in the presence of target nucleic acid molecules. Probes of the embodiments ...