US Patent Issued to LOMA LINDA UNIVERSITY on April 15 for "Method for utilizing engineered dendritic cells to induce gut-homing regulatory T cells and treat gut inflammation" (California Inventors)

ALEXANDRIA, Va., June 5 -- United States Patent no. 12,275,961, issued on April 15, was assigned to LOMA LINDA UNIVERSITY (Loma Linda, Calif.).

"Method for utilizing engineered dendritic cells to induce gut-homing regulatory T cells and treat gut inflammation" was invented by Xiaolei Tang (Loma Linda, Calif.), David J. Baylink (Redlands, Calif.), K.-H. William Lau (Redlands, Calif.) and Michael Walter (Loma Linda, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Gene-modified, lymphoid-tissue-homing dendritic cells that comprise a 1-alpha-hydroxylase gene and a retinaldehyde dehydrogenase 2 gene, where the 1-alpha-hydroxylase gene is expressed to produce functional 1-alpha-hydroxylase enzyme and the ret...