ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,491,198, issued on Dec. 9, was assigned to LKF21 LLC (New York).

"Doxycycline injection for sclerotherapy of lower eyelid festoons and malar edema" was invented by Robert Freund (New York).

According to the abstract* released by the U.S. Patent & Trademark Office: "Doxycycline injections improve the appearance of cosmetically significant lower eyelid festoons and malar edema, as well as of the jowls. The doxycycline is also useful for reducing edema of turbinates, the nasal concha or conchae shell-shaped networks of bones, vessels, and tissue within the nasal passageways that are responsible for warming, humidifying, and filtering the air as it is inhaled. The doxycline, in a concentr...