US Patent Issued to Life Technologies on July 22 for "Serum-free suspension system for lentiviral production" (Chinese, American Inventors)

ALEXANDRIA, Va., July 23 -- United States Patent no. 12,365,919, issued on July 22, was assigned to Life Technologies Corp. (Carlsbad, Calif.).

"Serum-free suspension system for lentiviral production" was invented by Xin Yu (Suzhou, China) and Xavier de Mollerat du Jeu (Encinitas, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A lentiviral vector production system comprises (a) a lentiviral culture supplement to control cell growth, (b) a transfection reagent comprising DHDMS, DOPE, and cholesterol to increase transfection efficiency, (c) a lentiviral production enhancer comprising sodium propionate, sodium butyrate, and caffeine to boost lentiviral production, wherein the lentiviral vector production...