US Patent Issued to Life Edit Therapeutics on June 24 for "RNA-guided nucleases and active fragments and variants thereof and methods of use" (North Carolina Inventors)

ALEXANDRIA, Va., June 25 -- United States Patent no. 12,338,455, issued on June 24, was assigned to Life Edit Therapeutics Inc. (Durham, N.C.).

"RNA-guided nucleases and active fragments and variants thereof and methods of use" was invented by Alexandra Briner Crawley (Cary, N.C.), Rodolphe Barrangou (Raleigh, N.C.), Tyson D. Bowen (Morrisville, N.C.), Michael Coyle (Chapel Hill, N.C.) and Tedd D. Elich (Durham, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods for binding to a target sequence of interest are provided. The compositions find use in cleaving or modifying a target sequence of interest, visualization of a target sequence of interest, and modifying the expression of a s...