ALEXANDRIA, Va., June 5 -- United States Patent no. 12,275,788, issued on April 15, was assigned to Legend Biotech Ireland Ltd. (Dublin).
"Single-domain antibodies against CD33 and constructs thereof" was invented by Yafeng Zhang (Jiangsu, China), Tailan Zhan (Jiangsu, China), Fei Sun (Jiangsu, China), Jian Liu (Jiangsu, China), Qing Zhang (Jiangsu, China) and Shu Wu (Jiangsu, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present application provides single-domain antibodies targeting CD33 and constructs thereof, including chimeric receptors, immune effector cell engagers and immunoconjugates. Further provided are engineered immune cells (such as T cells) comprising an anti-CD33 chimeric receptor ...