ALEXANDRIA, Va., June 4 -- United States Patent no. 12,318,395, issued on June 3, was assigned to LABORATORIOS LEON FARMA S.A. (Villaquilambre, Spain).
"Ethinyl estradiol-Beta-cyclodextrin complex and process for preparing thereof" was invented by Andreza Maria Ribeiro (Villaquilambre, Spain) and Maria Dolores Moya Ortega (Villaquilambre, Spain).
According to the abstract* released by the U.S. Patent & Trademark Office: "The process comprises combining prepared Beta-cyclodextrin solution and prepared ethinyl estradiol solution, then removing the solvent by spray-drying for obtaining an ethinyl estradiol Beta-cyclodextrin complex. The obtainable amorphous ethinyl estradiol Beta-cyclodextrin complex is suitable for use in pharmaceutical com...