ALEXANDRIA, Va., June 4 -- United States Patent no. 12,318,478, issued on June 3, was assigned to Laboratorios Farmaceuticos Rovi S.A. (Madrid).

"Risperidone or paliperidone implant formulation" was invented by Ibon Gutierro Aduriz (Granada, Spain) and Guillermo Franco Rodriguez (Madrid).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is directed to an injectable intramuscular depot composition suitable for forming an in situ solid implant in a body, comprising a drug which is risperidone and/or paliperidone or any pharmaceutically acceptable salt thereof in any combination, a biocompatible copolymer based on lactic and glycolic acid having a monomer ratio of lactic to glycolic acid of ab...