US Patent Issued to L.E.A.F. HOLDINGS GROUP on May 27 for "Alpha polyglutamated aminopterin and uses thereof" (Pennsylvania, New Jersey Inventors)

ALEXANDRIA, Va., June 17 -- United States Patent no. 12,310,966, issued on May 27, was assigned to L.E.A.F. HOLDINGS GROUP LLC (Gulph Mills, Pa.).

"Alpha polyglutamated aminopterin and uses thereof" was invented by Clet Niyikiza (Gulph Mills, Pa.) and Victor Mandla Moyo (Ringoes, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure relates generally to alpha polyglutamated aminopterin, formulations containing liposomes filled with alpha polyglutamated aminopterin, methods of making the alpha polyglutamated aminopterin and liposome containing formulations, and methods of using polyglutamated alpha polyglutamated aminopterin and liposome containing formulations to treat hyperproliferative disorde...