ALEXANDRIA, Va., March 12 -- United States Patent no. 12,246,019, issued on March 11, was assigned to L.E.A.F. HOLDINGS GROUP LLC (Gulph Mills, Pa.).

"Alpha polyglutamated lometrexol and uses thereof" was invented by Clet Niyikiza (Gulph Mills, Pa.) and Victor Mandla Moyo (Ringoes, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure relates generally to alpha polyglutamated lometrexol, formulations containing liposomes filled with alpha polyglutamated lometrexol, methods of making the alpha polyglutamated lometrexol and liposome containing formulations, and methods of using polyglutamated alpha polyglutamated lometrexol and liposome containing formulations to treat hyperproliferative disorders...