US Patent Issued to L.E.A.F. HOLDINGS GROUP on Feb. 11 for "Gamma polyglutamated antifolates and uses thereof" (Pennsylvania, New Jersey Inventors)

ALEXANDRIA, Va., Feb. 12 -- United States Patent no. 12,220,431, issued on Feb. 11, was assigned to L.E.A.F. HOLDINGS GROUP LLC (Gulph Mills, Pa.).

"Gamma polyglutamated antifolates and uses thereof" was invented by Clet Niyikiza (Gulph Mills, Pa.) and Victor Mandla Moyo (Ringoes, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure relates generally to gamma polyglutamated Antifolate, formulations containing liposomes filled with gamma polyglutamated Antifolate, methods of making the gamma polyglutamated Antifolate and liposome containing formulations, and methods of using polyglutamated gamma polyglutamated Antifolate and liposome containing formulations to treat hyperproliferative disorders ...