ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,413, issued on March 25, was assigned to KYOWA KIRIN Co. LTD. (Tokyo).

"Bispecific antibody binding to TfR" was invented by Keisuke Mitamura (Tokyo), Ryosuke Nakano (Tokyo), Masayuki Kai (Tokyo) and Nobuaki Takahashi (Tokyo).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a bispecific antibody in which an N-terminal side polypeptide is bound to an IgG portion that binds to TfR, a bispecific antibody fragment thereof, a DNA encoding the bispecific antibody or the bispecific antibody fragment thereof, a vector containing the DNA, a hybridoma and a transformant that produce the bispecific antibody or the bispecific antib...