US Patent Issued to KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY on Nov. 25 for "Protein that simultaneously and potently binds to both MCL-1 and BCL-xL and uses thereof" (South Korean Inventors)

ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,479,889, issued on Nov. 25, was assigned to KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (Daejeon, South Korea).

"Protein that simultaneously and potently binds to both MCL-1 and BCL-xL and uses thereof" was invented by Byung-Ha Oh (Daejeon, South Korea) and Seonghoon Kim (Daejeon, South Korea).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a protein that simultaneously binds to both MCL-1 and BCL-xL and uses thereof. The protein of the present invention simultaneously and specifically binds to both MCL-1 and BCL-xL, which are anti-apoptotic BCL-2 family proteins whose expression is increased in various carcinomas, ...