ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,454,563, issued on Oct. 28, was assigned to Kite Pharma Inc. (Santa Monica, Calif.).
"Immune cell function" was invented by Ruth E. Winter (Oakland, Calif.) and Saikat Banerjee (Oakland, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to the field of cell therapy, and more specifically, to improving CAR and/or TCR function through improvement of cytokine signaling. Disclosed are embodiments of a membrane bound interleukin 15 (IL-15)-IL-15Ralpha sushi domain chimeric receptor. The chimeric receptor may comprise a FAS transmembrane domain or an IL-7 transmembrane domain. Different embodiments of the chimeric receptor h...