US Patent Issued to Kite Pharma on Nov. 4 for "Modified chimeric antigen receptors and methods of use" (California, Massachusetts Inventors)

ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,459,979, issued on Nov. 4, was assigned to Kite Pharma Inc. (Santa Monica, Calif.).

"Modified chimeric antigen receptors and methods of use" was invented by Stuart A. Sievers (Van Nuys, Calif.) and Jed J. w. Wiltzius (Winchester, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure provides a chimeric antigen receptor (CAR) comprising a modified hinge, transmembrane and/or intracellular domain disclosed herein. Some aspects of the disclosure relate to a polynucleotide encoding a chimeric antigen receptor (CAR) comprising the costimulatory domain disclosed herein. Other aspects of the disclosure relate to cells comprising the CAR and use in...