US Patent Issued to Kiniksa Pharmaceuticals on Dec. 23 for "Formulations of anti-interleukin 1 receptor 1 antibodies" (Massachusetts Inventors)

ALEXANDRIA, Va., Dec. 23 -- United States Patent no. 12,502,352, issued on Dec. 23, was assigned to Kiniksa Pharmaceuticals GmbH (Zug, Switzerland).

"Formulations of anti-interleukin 1 receptor 1 antibodies" was invented by Ajit D'Souza (Lexington, Mass.) and Jianwen Xu (Lexington, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides, among other things, stable formulations comprising an anti-Interleukin 1 Receptor 1 (IL1R1) antibody at a concentration of greater than 80 mg/ml with a pH ranging from 4.4-5.7, wherein the amount of HMW species in the formulation increases less than 2% upon storage at 25deg C. for at least 4 weeks."

The patent was filed on July 21, 2025, under Ap...