US Patent Issued to King's College London on Dec. 30 for "Therapeutic agents" (British Inventors)

ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,509,499, issued on Dec. 30, was assigned to King's College London (London).

"Therapeutic agents" was invented by John Maher (London), Daniela Yordanova Achkova (London), Lynsey May Whilding (London) and Benjamin Owen Draper (London).

According to the abstract* released by the U.S. Patent & Trademark Office: "An immunoresponsive cell, such as a T-cell expressing a second generation chimeric antigen receptor comprising: (a) a signalling region; (b) a co-stimulatory signalling region; (c) a transmembrane domain; and (d) a binding element that specifically interacts with a first epitope on a target antigen; and a chimeric costimulatory receptor comprising (e) a co-stimulatory signalling ...