US Patent Issued to KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY on Jan. 13 for "Compositions and methods of targeted nucleic acid enrichment by loop adapter protection and exonuclease digestion" (Saudi Arabia Inventors)

ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,522,857, issued on Jan. 13, was assigned to KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (Thuwal, Saudi Arabia).

"Compositions and methods of targeted nucleic acid enrichment by loop adapter protection and exonuclease digestion" was invented by Mo Li (Thuwal, Saudi Arabia), Chongwei Bi (Thuwal, Saudi Arabia) and Lin Wang (Thuwal, Saudi Arabia).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods for enriching DNA from any loci of interest are provided. Endonuclease(s) such as RNA-guided nucleases Cpf1/Cas9 can cut the flanking regions of the gene of interest in, for example genomic DNA, followed by ligation of loop adapters. The ...