ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,440,539, issued on Oct. 14, was assigned to Keros Therapeutics Inc. (Lexington, Mass.).

"Methods of using activin receptor type IIB variants" was invented by Jasbir S. Seehra (Lexington, Mass.), Jennifer Lachey (Lincoln, Mass.) and Elissa Furutani (Belmont, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention features polypeptides that include an extracellular ActRIIB variant. In some embodiments, a polypeptide of the invention includes an extracellular ActRIIB variant fused to an Fc domain monomer or moiety. The invention also features pharmaceutical compositions containing said polypeptides and methods of using the polypeptides to treat ...