US Patent Issued to Keros Therapeutics on July 8 for "Activin receptor type IIa variants and methods of use thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., July 9 -- United States Patent no. 12,350,313, issued on July 8, was assigned to Keros Therapeutics Inc. (Lexington, Mass.).

"Activin receptor type IIa variants and methods of use thereof" was invented by Jasbir S. Seehra (Lexington, Mass.) and Jennifer Lachey (Lincoln, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention features polypeptides that include an extracellular ActRIIa variant. In some embodiments, a polypeptide of the invention includes an extracellular ActRIIa variant fused to an Fc domain monomer or moiety. The invention also features pharmaceutical compositions and methods of using the polypeptides to treat diseases and conditions involving weakness and atrophy ...