US Patent Issued to Katholieke Universiteit Leuven on Nov. 11 for "Functional cure of retroviral infection" (Belgian Inventors)

ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,465,604, issued on Nov. 11, was assigned to Katholieke Universiteit Leuven (Leuven, Belgium).

"Functional cure of retroviral infection" was invented by Frauke Christ (Leuven, Belgium), Zeger Debyser (Heverlee, Belgium), Rik Gijsbers (Blanden, Belgium) and Lenard Vranckx (Hulshout, Belgium).

According to the abstract* released by the U.S. Patent & Trademark Office: "The application relates to methods of curing retroviral infections, i.e. ensuring remission of retroviral infections, more particularly HIV infections, by administering a compound which is capable of binding to the LEDGF/p75 binding pocket of HIV-integrase and inhibiting LEDGF/p75-IN protein-protein interaction. The applic...