ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,545,709, issued on Feb. 10, was assigned to KATHOLIEKE UNIVERSITEIT LEUVEN (Leuven, Belgium).
"Chimeric filovirus vaccines" was invented by Kai Dallmeier (Kessel-Lo, Belgium), Lorena Sanchez Felipe (Wijgmaal, Belgium), Viktor Lemmens (Leuven, Belgium) and Johan Neyts (Kessel-Lo, Belgium).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to polynucleotides comprising a sequence of a live, infectious, attenuated Flavivirus wherein a nucleotide sequence encoding at least a part of a Filovirus glycoprotein is located at the intergenic region between the E and NS1 gene of said Flavivirus, such that a chimeric virus is expressed, cha...