ALEXANDRIA, Va., March 26 -- United States Patent no. 12,257,289, issued on March 25, was assigned to KaloCyte Inc. (Baltimore).
"Self-assembling oxygen carrier compositions" was invented by Dipanjan Pan (Ellicot City, Md.), Allan Doctor (Towson, Md.) and Philip C. Spinella (Chesterfiled, Mo.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Synthetic blood substitutes and methods for making them. A lipid-amphiphile blood-substitute precursor compound having a hydrophobic fatty acid/acyl moiety, a hydrophilic head moiety including a phosphate group, and a pH responsive moiety. The lipid-amphiphile precursor is configured to self-assemble from a solution mixture of phospholipid and cholesterol in the presence of...