US Patent Issued to KaliVir Immunotherapeutcs on Sept. 2 for "Oncolytic immunotherapy by tumor micro-environment remodeling" (Pennsylvania Inventors)

ALEXANDRIA, Va., Sept. 3 -- United States Patent no. 12,403,165, issued on Sept. 2, was assigned to KaliVir Immunotherapeutcs Inc. (Pittsburgh).

"Oncolytic immunotherapy by tumor micro-environment remodeling" was invented by Stephen Howard Thorne (Pittsburgh), Mingrui Zhang (Pittsburgh) and Daniel J. Byrd (Pittsburgh).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure relates to modified oncolytic viruses. The modified oncolytic viruses of the disclosure comprise modification in the viral genome encoding exogenous nucleic acids to enhance the oncolytic immunotherapy by remodeling the tumor microenvironment and with enhanced systemic delivery. The disclosure further relates to compositions comprisin...