ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,421,225, issued on Sept. 23, was assigned to KAKEN PHARMACEUTICAL Co. LTD. (Tokyo).
"Heteroaromatic amide derivative and medicament containing the same" was invented by Issei Akahoshi (Kyoto, Japan), Yoshitake Sumikawa (Kyoto, Japan), Sadayoshi Furuta (Tokyo), Keiichiro Fukushima (Kyoto, Japan), Takuya Imazu (Kyoto, Japan) and Ryota Kotaka (Kyoto, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "A heteroaromatic amide derivative or salt thereof showing high efficacy for diseases associated with Nav1.7 is represented by general formula (I) wherein, X1-X2 is N-C or C-N, Y1, Y2, Y3 and Y4 are -CH2-, -CR4aH- or -O- and so on, Z1 is -O- and so on, ring ...