US Patent Issued to JUVENA THERAPEUTICS on June 17 for "Regenerative polypeptides and uses thereof" (California Inventors)

ALEXANDRIA, Va., June 19 -- United States Patent no. 12,329,801, issued on June 17, was assigned to JUVENA THERAPEUTICS INC. (Redwood City, Calif.).

"Regenerative polypeptides and uses thereof" was invented by Hanadie Yousef (Palo Alto, Calif.), Jeremy O'Connell (Palo Alto, Calif.), Thach Mai (South San Francisco, Calif.) and Zhihua Li (San Jose, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are polypeptides with an IGF2 amino acid sequence and an amino acid sequence from a heterologous polypeptide for treatment of soft-tissue and muscle diseases, disorders, and injuries. Mutations within the IGF2 amino acid sequence improved stability by reducing backbone cleavage. Synergistic combi...