ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,428,624, issued on Sept. 30, was assigned to Juntendo Educational Foundation (Tokyo).

"Method for producing pancreatic endocrine cells" was invented by Masahito Matsumoto (Tokyo), Yasushi Okazaki (Tokyo) and Izumi Sugahara (Tokyo).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for producing pancreatic endocrine cells, including introducing (B) or (D) below into cultured somatic cells to transdifferentiate into a population of pancreatic endocrine cells that include insulin-producing beta-cells: (B) a GLIS1 gene or one or more gene products thereof, a Neurogenin3 gene or one or more gene products thereof, and a Pdx1 gene or one or more gene prod...