ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,475, issued on May 13, was assigned to Johann Wolfgang Goethe-Universitat Frankfurt am Main (Germany).
"System for the assembly and modification of non-ribosomal peptide synthases" was invented by Helge B. Bode (Oberursel, Germany), Kenan Bozhuyuk (Frankfurt am Main, Germany) and Annabell Linck (Frankfurt am Main, Germany).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention pertains to a system for the assembly and modification of non-ribosomal peptide synthases (NRPS). The system uses novel well defined building blocks (units) comprising condensation subdomains. This strategy allows for the efficient combination of assembly units re...