US Patent Issued to JN BIOSCIENCES on Dec. 9 for "Multimeric hybrid Fc proteins for replacement of IVIG" (California Inventors)

ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,492,231, issued on Dec. 9, was assigned to JN BIOSCIENCES LLC (Mountain View, Calif.).

"Multimeric hybrid Fc proteins for replacement of IVIG" was invented by Naoya Tsurushita (Mountain View, Calif.) and J. Yun Tso (Mountain View, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The hybrid Fc proteins of this invention include IgG and IgM Fc components. The IgG Fc component includes at least a portion of a hinge region and CH2 and CHS regions. The IgM component includes CMu3 and CMu4 regions of a CMu constant region. The hybrid Fc proteins can form duplexes by interchain disulfide bonding between cysteines in their hinge regions. The hybrid Fc prote...