ALEXANDRIA, Va., Dec. 23 -- United States Patent no. 12,503,516, issued on Dec. 23, was assigned to JJP Biologics SP. Z O.O. (Warsaw, Poland).
"Anti-human HVEM (TNFRSF14) antibodies and uses thereof" was invented by Louis Boon (Badhoevedorp, Netherlands), Petrus Johannes Simons (Hillegom, Netherlands) and Marcel Theodorus Den Hartog (Monnickendam, Netherlands).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention discloses an antibody that binds an extracellular part of human HVEM on human HVEM-expressing cells, that prevents binding of BTLA to HVEM when the antibody is bound to said extracellular part of HVEM, wherein said antibody displaces BTLA bound to said extracellular part of HVEM. The invention...