ALEXANDRIA, Va., June 6 -- United States Patent no. 12,281,177, issued on April 22, was assigned to JIANGSU ALPHAMAB BIOPHARMACEUTICALS Co. LTD. (Jiangsu, China) and SUZHOU ALPHAMAB Co. LTD. (Jiangsu, China).
"Heterodimer molecule based on CH3 domain, and preparation method and use thereof" was invented by Ting Xu (Jiangsu, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure is directed to a heterodimer molecule, comprising a first polypeptide chain and a second polypeptide chain, and the first polypeptide chain comprises a first CH3 domain of an antibody heavy chain constant region, the second polypeptide chain comprises a second CH3 domain of an antibody heavy chain constant region. Compari...