ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,534,753, issued on Jan. 27, was assigned to JIANGNAN UNIVERSITY (Wuxi, China).

"Method for improving specificity and affinity of aptamer by molecular design guidance" was invented by Xiaole Xia (Wuxi, China), Yue Zhang (Wuxi, China), Ling Gao (Wuxi, China), Mengfei Long (Wuxi, China), Qingtong Zhou (Wuxi, China) and Jingwen Zhou (Wuxi, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to the technical field of bioengineering and provides a method for improving the specificity and affinity of an aptamer. The method includes: S1, screening a target of an aptamer from a compound information database by virtual computing; S2, verify...