US Patent Issued to Jazz Pharmaceuticals Ireland on May 20 for "Fused bicyclic RAF inhibitors and methods for use thereof" (British Inventors)

ALEXANDRIA, Va., June 16 -- United States Patent no. 12,304,912, issued on May 20, was assigned to Jazz Pharmaceuticals Ireland Ltd. (Dublin).

"Fused bicyclic RAF inhibitors and methods for use thereof" was invented by Andrew Belfield (Macclesfield, Great Britain), Clifford David Jones (Macclesfield, Great Britain), Jean-Francois Margathe (Macclesfield, Great Britain) and Chiara Colletto (Macclesfield, Great Britain).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure generally relates to improved synthesis of fused bicyclic Raf inhibitors of formula (I), (I-A), (I-B), (II), or (III), or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof. The disclosure also relates to met...