ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,492,182, issued on Dec. 9, was assigned to Japan Tobacco Inc. (Tokyo).
"Hydroxytriazine compounds and pharmaceutical use thereof" was invented by Ikuo Mitani (Osaka, Japan), Yutaro Hirono (Osaka, Japan) and Masaki Yamashita (Osaka, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a compound having an mPGES-1 inhibitory activity and useful for the prophylaxis or treatment of pain, rheumatism, osteoarthritis, fever, Alzheimer's disease, multiple sclerosis, arteriosclerosis, glaucoma, ocular hypertension, ischemic retinal disease, systemic scleroderma and/or cancer including colorectal cancer.The present invention relates ...