ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,408, issued on Oct. 21, was assigned to Japan Science and Technology Agency (Kawaguchi, Japan).
"Method for producing capped RNA" was invented by Hiroshi Abe (Nagoya, Japan), Yasuaki Kimura (Nagoya, Japan) and Naoko Abe (Nagoya, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "A method for producing a capped RNA which is an RNA having the 5'-end modified with a cap, the method including: reacting an activated capping compound represented by with a monophosphate RNA having the 5'-end monophosphorylated, where, L represents a leaving group. The activated capping compound is preferably a compound represented by"
The patent was filed on Feb. 19, 20...