US Patent Issued to JAPAN SCIENCE AND TECHNOLOGY AGENCY on June 24 for "Photoactivatable Tet expression control system" (Japanese Inventors)

ALEXANDRIA, Va., June 25 -- United States Patent no. 12,338,443, issued on June 24, was assigned to JAPAN SCIENCE AND TECHNOLOGY AGENCY (Saitama, Japan).

"Photoactivatable Tet expression control system" was invented by Itaru Imayoshi (Kyoto, Japan), Mayumi Yamada (Kyoto, Japan), Yusuke Suzuki (Kyoto, Japan) and Shinji Nagasaki (Kyoto, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a photoactivatable Tet-OFF/ON system that can precisely control temporal and spatial gene expression. The present invention is a PA-Tet-OFF/ON system that includes a target gene expression cassette including a TRE having a TetO sequence, a promoter which is controlled by the TRE, and a target ge...