US Patent Issued to Janssen Pharmaceuticals on June 17 for "Alphavirus-based replicons for administration of biotherapeutics" (California, Kansas Inventors)

ALEXANDRIA, Va., June 19 -- United States Patent no. 12,331,076, issued on June 17, was assigned to Janssen Pharmaceuticals Inc. (Titusville, N.J.).

"Alphavirus-based replicons for administration of biotherapeutics" was invented by Jason L. Dehart (San Diego), Nathaniel Stephen Wang (San Diego), Parinaz Aliahmad (San Diego), Shigeki Miyake-Stoner (La Jolla, Calif.) and Kurt Iver Kamrud (Olathe, Kan.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides RNA replicons useful for administering a heterologous protein or peptide into a mammal and eliciting a reduced immune response or no immune response from the mammal. The RNA replicons have RNA sequences encoding for a heterologous protein or pe...